Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 8/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709964 | 0.86 | SLC5A2 (0.49) | SLC5A2SLC5A1 | |
| B-D-Galactose SCHEMBL27634340 | 0.73 | SLC5A2 (0.49) | SLC5A2 | |
| SCHEMBL14087418 | 0.72 | IDO1 (0.39) | IDO1 | |
| SCHEMBL2947478 | 0.72 | IDO1 (0.39) | IDO1 | |
| SCHEMBL9133277 | 0.72 | IDO1 (0.39) | IDO1 | |
| SCHEMBL15820966 | 0.70 | SLC5A2 (0.51) | SLC5A2 | |
| SCHEMBL15820964 | 0.70 | SLC5A2 (0.51) | SLC5A2 | |
| SCHEMBL27709976 | 0.69 | SLC5A2 (0.47) | SLC5A2SLC5A1 | |
| SCHEMBL27730414 | 0.69 | TYR (0.55) | SLC5A2SLC5A1 | |
| SCHEMBL7147747 | 0.68 | SLC5A2 (0.53) | SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218732-A1 | Selective Inhibitors Of Protein Arginine Methyltransferase 5 (PRMT5) | PRELUDE THERAPEUTICS INCORPORATED | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218732-A1 | Selective Inhibitors Of Protein Arginine Methyltransferase 5 (PRMT5) | PRMT5, PRMT6, PRMT1 | SLC5A2 3932/4885SLC5A1 3640/4885SLC2A1 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.