Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | BRAF | P15056 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 5/20 | 0.45 |
| ▸ | LCK | P06239 | 4/20 | 0.45 |
| ▸ | TEK | Q02763 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | BCR | P11274 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24626382 | 0.86 | KIT (0.57) | KITCSF1RCYP2C9BRAFKDR | |
| SCHEMBL29675114 | 0.85 | KIT (0.69) | KITCYP2C9KDRABL1FGFR1 | |
| SCHEMBL24626345 | 0.85 | KIT (0.69) | KITCYP2C9KDRABL1FGFR1 | |
| SCHEMBL24626007 | 0.83 | CSF1R (0.54) | KITCSF1RCYP2C9BRAFKDR | |
| SCHEMBL29675001 | 0.81 | CSF1R (0.66) | KITCSF1RCYP2C9KDRLCK | |
| SCHEMBL24626070 | 0.81 | CSF1R (0.66) | KITCSF1RCYP2C9KDRLCK | |
| SCHEMBL29675418 | 0.79 | KIT (0.72) | KITCYP2C9KDRABL1FGFR1 | |
| SCHEMBL24626254 | 0.79 | KIT (0.72) | KITCYP2C9KDRABL1FGFR1 | |
| SCHEMBL29675147 | 0.78 | ABL1 (0.63) | ABL1BCRSRC | |
| SCHEMBL24626419 | 0.78 | KIT (0.70) | KITCYP2C9ABL1FGFR1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |