SCHEMBL29675147

SCHEMBL29675147

Cc1cn(-c2cc(NC(=O)c3cc(C#Cc4cnc(N)c(Cl)c4)c(C)cc3F)cc(C(F)(F)F)c2)cn1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 13/20 0.63
BCR P11274 12/20 0.63
NR2E1 Q9Y466 6/20 0.56
SRC P12931 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24626580 0.89 ABL1 (0.61) ABL1BCRNR2E1SRC
SCHEMBL29675072 0.89 ABL1 (0.61) ABL1BCRNR2E1SRC
SCHEMBL29675330 0.87 ABL1 (0.83) ABL1BCRNR2E1SRC
SCHEMBL29675124 0.84 ABL1 (0.84) ABL1BCRNR2E1SRC
SCHEMBL24626536 0.84 ABL1 (0.84) ABL1BCRNR2E1SRC
SCHEMBL24626352 0.78 KIT (0.49) ABL1BCRSRC
SCHEMBL3428132 0.78 ABL1 (1.00) ABL1BCRNR2E1SRC
SCHEMBL29515144 0.78 ABL1 (1.00) ABL1BCRNR2E1SRC
SCHEMBL29675033 0.77 ABL1 (0.80) ABL1BCRNR2E1SRC
SCHEMBL29675148 0.77 ABL1 (0.68) ABL1BCRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022149855-A1 HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF 주식회사 비투에스바이오 2022-07-14 WO claimed
WO-2022149855-A1 HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF 주식회사 비투에스바이오 2022-07-14 WO disclosed