Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | PADI2 | Q9Y2J8 | 6/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174806 | 1.00 | PADI4 (0.42) | PADI4FOLH1DRD2DRD4PADI2 | |
| SCHEMBL30804858 | 1.00 | PADI4 (0.42) | PADI4FOLH1DRD2DRD4PADI2 | |
| SCHEMBL30665193 | 0.93 | PADI4 (0.43) | PADI4FOLH1PADI2MCHR1ATM | |
| SCHEMBL24627778 | 0.93 | PADI4 (0.43) | PADI4FOLH1PADI2MCHR1ATM | |
| SCHEMBL27174787 | 0.93 | PADI4 (0.43) | PADI4FOLH1PADI2MCHR1ATM | |
| SCHEMBL27174804 | 0.89 | PPARA (0.46) | PADI4PADI2MMP2PADI6 | |
| SCHEMBL24627792 | 0.89 | PPARA (0.46) | PADI4PADI2MMP2PADI6 | |
| SCHEMBL24627883 | 0.87 | MCHR1 (0.43) | PADI4FOLH1PADI2MCHR1MMP2 | |
| SCHEMBL30804864 | 0.87 | MCHR1 (0.43) | PADI4FOLH1PADI2MCHR1MMP2 | |
| SCHEMBL27174782 | 0.87 | MCHR1 (0.43) | PADI4FOLH1PADI2MCHR1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148457-A1 | SUBSTITUTED SALICYLAMIDE COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2022-07-14 | — | — | WO | disclosed |