Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.49 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.41 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804844 | 1.00 | KDM1A (0.49) | KDM1APADI6MMP2CTSVCTSL | |
| SCHEMBL27174800 | 1.00 | KDM1A (0.49) | KDM1APADI6MMP2CTSVCTSL | |
| SCHEMBL30804846 | 0.96 | KDM1A (0.44) | KDM1APADI6MMP2CTSVCTSL | |
| SCHEMBL24627795 | 0.96 | KDM1A (0.44) | KDM1APADI6MMP2CTSVCTSL | |
| SCHEMBL27174815 | 0.96 | KDM1A (0.44) | KDM1APADI6MMP2CTSVCTSL | |
| SCHEMBL27174817 | 0.93 | PSMB5 (0.44) | KDM1AMMP2CTSVCTSLCTSB | |
| SCHEMBL24627900 | 0.93 | PSMB5 (0.44) | KDM1AMMP2CTSVCTSLCTSB | |
| SCHEMBL24627792 | 0.93 | PPARA (0.46) | KDM1APADI6MMP2PSMB5PADI4 | |
| SCHEMBL27174804 | 0.93 | PPARA (0.46) | KDM1APADI6MMP2PSMB5PADI4 | |
| SCHEMBL24627791 | 0.92 | MMP2 (0.43) | KDM1APADI6MMP2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148457-A1 | SUBSTITUTED SALICYLAMIDE COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2022-07-14 | — | — | WO | disclosed |