Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.40 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174795 | 1.00 | MMP2 (0.41) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL30804863 | 1.00 | MMP2 (0.41) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL27174819 | 0.96 | MMP2 (0.43) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL24627791 | 0.96 | MMP2 (0.43) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL24627792 | 0.94 | PPARA (0.46) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL27174804 | 0.94 | PPARA (0.46) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL24627795 | 0.91 | KDM1A (0.44) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL30804846 | 0.91 | KDM1A (0.44) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL27174815 | 0.91 | KDM1A (0.44) | MMP2PADI6PPARAPPARGBRD4 | |
| SCHEMBL30804844 | 0.89 | KDM1A (0.49) | MMP2PADI6PPARAPPARGPADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148457-A1 | SUBSTITUTED SALICYLAMIDE COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2022-07-14 | — | — | WO | disclosed |