SCHEMBL24627909

SCHEMBL24627909

CC1(C)c2ccccc2-c2cc3c(cc21)c(-c1cccc(-c2ccccc2)c1)cc1ccc(-c2ccc4c(c2)c2ccccc2n4-c2ccccc2)cc13

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSPO P30536 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725784 0.91 KDM4E (0.38) KDM4EATML3MBTL1PTGER4
SCHEMBL17878950 0.89 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17069909 0.87 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL16641281 0.87 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17878959 0.86 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17878941 0.86 KDM4E (0.40) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17878954 0.86 KDM4E (0.40) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17069908 0.86 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL15946301 0.85 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL14822517 0.85 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed