SCHEMBL24628247

SCHEMBL24628247

c1ccc(-c2ccc(-c3nc(-c4ccc5c(c4)oc4ccccc45)nc(-c4ccc5c6ccccc6c6cccc7oc4c5c76)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
POLB P06746 2/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ALOX5 P09917 2/20 0.38
TSHR P16473 3/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 3/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK1 P28482 1/20 0.36
CDC14B O60729 1/20 0.36
CDC14A Q9UNH5 1/20 0.36
AHR P35869 1/20 0.36
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36
KMT2A Q03164 2/20 0.35
USP2 O75604 1/20 0.35
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24628293 0.92 MAPT (0.41) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24628577 0.90 MAPT (0.39) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24628071 0.90 MAPT (0.39) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL25645985 0.90 MAPT (0.41) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL23820199 0.89 CDC14B (0.42) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL23821650 0.89 CDC14B (0.42) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL25645777 0.89 ALOX5 (0.49) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL22377126 0.88 ALOX5 (0.39) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24215873 0.88 ALOX5 (0.43) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL22763997 0.88 ALOX5 (0.43) MAPTALDH1A1KDM4EPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed