Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PKLR | P30613 | 2/20 | 0.57 |
| ▸ | GALNT2 | Q10471 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ellagic Acid SCHEMBL29439360 | 0.76 | KDM4E (1.00) | KDM4EMAPTAPEX1RECQLTDP1 | |
| Ellagic Acid SCHEMBL30475160 | 0.76 | KDM4E (1.00) | KDM4EMAPTAPEX1RECQLTDP1 | |
| Ellagic Acid SCHEMBL28824363 | 0.73 | KDM4E (0.92) | KDM4EMAPTAPEX1RECQLTDP1 | |
| Demannose SCHEMBL15559865 | 0.71 | LMNA (0.42) | KDM4ETDP1GAALMNAUSP2 | |
| Demannose SCHEMBL2856676 | 0.71 | LMNA (0.55) | KDM4ETDP1LMNAUSP2AKR1B1 | |
| Demannose SCHEMBL1812 | 0.69 | LMNA (0.58) | KDM4EMAPTTDP1LMNAUSP2 | |
| Demannose SCHEMBL13947310 | 0.69 | LMNA (0.58) | KDM4EMAPTTDP1LMNAUSP2 | |
| Demannose SCHEMBL6529193 | 0.69 | LMNA (0.58) | KDM4EMAPTTDP1LMNAUSP2 | |
| Demannose SCHEMBL2290731 | 0.69 | LMNA (0.58) | KDM4EMAPTTDP1LMNAUSP2 | |
| Demannose SCHEMBL20956808 | 0.69 | LMNA (0.58) | KDM4EMAPTTDP1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2663342-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | Allergan, Inc. (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-2544652-A2 | A FLUID COMPOSITION COMPRISING A HYALURONAN POLYMER AND MANNITOL FOR IMPROVING SKIN CONDITION. | Allergan Industrie SAS (FR) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012097272-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN, INC. (US) | 2012-07-19 | — | — | WO | disclosed |
| WO-2011110894-A2 | FLUID COMPOSITION FOR IMPROVING SKIN CONDITIONS | ALLERGAN INDUSTRIE SAS (FR) | 2011-09-15 | — | — | WO | disclosed |