SCHEMBL24628907

SCHEMBL24628907

CN/C(=C\C(=N)c1ccc2c(c1)oc1ccccc12)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.44
HTR2B P41595 1/20 0.43
AHR P35869 2/20 0.38
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 3/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21583592 0.83 HTR2B (0.49) TTRHTR2BAHRNPC1RAB9A
SCHEMBL14979452 0.77 F2 (0.41) SMN1; SMN2MEN1KMT2AGAAALDH1A1
SCHEMBL24628810 0.76 PRSS1 (0.34)
SCHEMBL27323906 0.75 TTR (0.49) TTRHTR2BAHRNPC1RAB9A
SCHEMBL14979466 0.73 WDR5 (0.47) NPC1RAB9ASMN1; SMN2MAPTPOLB
SCHEMBL23869908 0.73 TTR (0.53) TTRHTR2BAHRNPC1RAB9A
SCHEMBL21092263 0.71 HTR2B (0.48) TTRHTR2BAHRNPC1RAB9A
SCHEMBL3066191 0.70 TTR (0.50) TTRHTR2BAHRNPC1RAB9A
SCHEMBL21474012 0.70 HTR2B (0.47) TTRHTR2BAHRNPC1RAB9A
SCHEMBL24443206 0.69 TTR (0.47) TTRHTR2BAHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed