Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.83 |
| ▸ | NPC1 | O15118 | 6/20 | 0.83 |
| ▸ | ATM | Q13315 | 2/20 | 0.83 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | RAD52 | P43351 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064445 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1ATMRAB9A | |
| SCHEMBL3363229 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1ATMRAB9A | |
| SCHEMBL8651550 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1ATMRAB9A | |
| SCHEMBL8007458 | 0.98 | MEN1 (0.86) | MEN1KMT2ANPC1ATMRAB9A | |
| SCHEMBL27561681 | 0.86 | MEN1 (0.83) | MEN1KMT2ANPC1ATMRAB9A | |
| SCHEMBL10595582 | 0.84 | MEN1 (0.60) | MEN1KMT2ANPC1ATMRAB9A | |
| Iodide SCHEMBL17423284 | 0.82 | MEN1 (1.00) | MEN1KMT2ANPC1ATMRAB9A | |
| SCHEMBL9704067 | 0.81 | KDM4E (0.60) | MEN1KMT2ANPC1ATMRAB9A | |
| Iodide SCHEMBL8917095 | 0.80 | MEN1 (0.58) | MEN1KMT2ANPC1ATMRAB9A | |
| Iodide SCHEMBL8920749 | 0.80 | MEN1 (0.63) | MEN1KMT2ANPC1ATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013112-B2 | Brain natriuretic peptide matrix for use in diagnosis of congestive heart failure | ABBOTT LABORATORIES (US) | 2011-09-06 | — | — | US | disclosed |
| EP-2069384-A2 | BIOMARKER FRAGMENTS FOR THE DETECTION OF HUMAN BNP | Abbott Laboratories (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080248491-A1 | BIOMARKER FRAGMENTS FOR THE DETECTION OF HUMAN BNP | ABBOTT LABORATORIES | 2008-10-09 | — | — | US | disclosed |
| US-20080064045-A1 | Using increased presence of brain natriuretic peptide (BNP) as diagnostic indicator of congestive heart failure | ABBOTT LABORATORIES | 2008-03-13 | — | — | US | disclosed |
| WO-2008030901-A2 | BIOMARKER FRAGMENTS FOR THE DETECTION OF HUMAN BNP | ABBOTT LABORATORIES (US) | 2008-03-13 | — | — | WO | disclosed |