Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462923 | 0.80 | MEN1 (0.83) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL3363229 | 0.80 | MEN1 (0.83) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL8651550 | 0.80 | MEN1 (0.83) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL9064445 | 0.80 | MEN1 (0.83) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL8007458 | 0.78 | MEN1 (0.86) | MEN1KMT2AATMNPC1RAB9A | |
| Iodide SCHEMBL17423284 | 0.73 | MEN1 (1.00) | MEN1KMT2AATMNPC1RAB9A | |
| Iodide SCHEMBL8917095 | 0.72 | MEN1 (0.58) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL16859491 | 0.72 | ATM (0.65) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL11949199 | 0.71 | TERT (0.42) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL27561681 | 0.70 | MEN1 (0.83) | MEN1KMT2AATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665328-A | USING SELECTED DYE AS BINDING AGENT WITHOUT PRODUCING DETRIMENTAL EFFECT ON MORPHOLOGY OR PHYSIOLOGICAL FUNCTION OF CELLS | PHANOS TECHNOLOGIES, INC. (US) | 1997-09-09 | — | — | US | disclosed |