Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 9/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13209051 | 0.85 | POLB (0.47) | P2RX7PARP1NOTUMPOLBPDK2 | |
| SCHEMBL17232814 | 0.84 | P2RX7 (0.48) | P2RX7PARP1NOTUMPOLBPDK2 | |
| SCHEMBL16219061 | 0.80 | P2RX7 (0.45) | P2RX7PARP1NOTUMPOLBPDK2 | |
| SCHEMBL13245865 | 0.80 | NOTUM (0.47) | P2RX7PARP1NOTUMPOLBPDK2 | |
| SCHEMBL25430234 | 0.75 | NOTUM (0.43) | P2RX7NOTUMPOLBPDK2TACR3 | |
| SCHEMBL13209040 | 0.72 | POLB (0.49) | P2RX7PARP1NOTUMPOLBCYP1A2 | |
| SCHEMBL8034374 | 0.70 | POLB (0.48) | P2RX7NOTUMPOLB | |
| SCHEMBL21253359 | 0.70 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL21253334 | 0.67 | P2RX7 (0.80) | P2RX7 | |
| SCHEMBL17232706 | 0.67 | POLB (0.42) | P2RX7NOTUMPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150707-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, Inc. (US) | 2022-07-14 | — | — | WO | disclosed |