SCHEMBL24630324

SCHEMBL24630324

COC(=O)[C@]1(Sc2ccc(C)cc2)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O)O1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 2/20 0.35
▸ POLB P06746 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ ABCB1 P08183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29332992 0.94 POLB (0.30) POLBMAPK1
SCHEMBL29332607 0.94 POLB (0.30) POLBMAPK1
SCHEMBL31695277 0.92 ABCB1 (0.30) ABCB1
SCHEMBL24630168 0.92 ABCB1 (0.30) ABCB1
SCHEMBL24630222 0.86 — —
SCHEMBL24630325 0.86 — —
SCHEMBL31695118 0.85 LMNA (0.31) —
SCHEMBL27390994 0.83 POLB (0.31) POLBMAPK1
SCHEMBL29326715 0.83 — —
SCHEMBL29332401 0.82 CD22 (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
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