Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284004 | 0.94 | DRD2 (0.38) | DRD2SIGMAR1KDM4EOPRD1KCNJ1 | |
| SCHEMBL13412948 | 0.78 | DRD2 (0.36) | DRD2SIGMAR1OPRD1KCNJ1KCNH2 | |
| SCHEMBL11575106 | 0.78 | — | — | |
| SCHEMBL15348806 | 0.78 | KDM4E (0.42) | KDM4EGPR183MEN1KMT2A | |
| SCHEMBL2738294 | 0.76 | DAO (0.43) | DRD2SIGMAR1OPRD1KCNH2DRD3 | |
| SCHEMBL12850091 | 0.76 | KDM4E (0.37) | KDM4EGPR183MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1920270 | 0.76 | KDM4E (0.33) | KDM4EKCNJ1KCNH2GPR183MEN1 | |
| SCHEMBL27279915 | 0.74 | CARM1 (0.52) | SIGMAR1 | |
| SCHEMBL20254465 | 0.74 | DAO (0.46) | DRD2SIGMAR1OPRD1KCNH2DRD3 | |
| SCHEMBL18500499 | 0.74 | DRD2 (0.39) | DRD2SIGMAR1KDM4EOPRD1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150555-A2 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2022-07-14 | — | — | WO | disclosed |