Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.43 |
| ▸ | ACACA | Q13085 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631825 | 1.00 | ACACB (0.43) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL30134736 | 1.00 | ACACB (0.43) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL24631671 | 0.90 | ACACB (0.42) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL30134797 | 0.90 | ACACB (0.42) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL24631462 | 0.90 | ACACB (0.42) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL30134766 | 0.86 | ACACB (0.41) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL30134764 | 0.86 | ACACB (0.41) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL24631674 | 0.86 | ACACB (0.41) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL24631670 | 0.86 | ACACB (0.41) | ACACBACACADRD2NAMPTCKS1B | |
| SCHEMBL24631608 | 0.78 | DRD2 (0.40) | ACACBACACADRD2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217265-A1 | TAAR1 AND SEROTONIN MODULATORS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |