Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 19/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 16/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174081 | 1.00 | F11 (0.41) | F11KLKB1CYP3A4PTGS2 | |
| SCHEMBL24633366 | 0.88 | NOTUM (0.39) | F11KLKB1CYP3A4 | |
| SCHEMBL31174105 | 0.88 | NOTUM (0.39) | F11KLKB1CYP3A4 | |
| SCHEMBL29227926 | 0.88 | P4HTM (0.38) | F11KLKB1CYP3A4PTGS2 | |
| SCHEMBL24633361 | 0.84 | F11 (0.41) | F11KLKB1CYP3A4 | |
| SCHEMBL21357358 | 0.83 | F11 (0.49) | F11KLKB1CYP3A4 | |
| SCHEMBL29479321 | 0.83 | F11 (0.49) | F11KLKB1CYP3A4 | |
| SCHEMBL31174048 | 0.81 | F11 (0.38) | F11KLKB1CYP3A4 | |
| SCHEMBL31174076 | 0.81 | F11 (0.38) | F11KLKB1CYP3A4 | |
| SCHEMBL31174040 | 0.81 | ALDH2 (0.33) | F11KLKB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222960-A1 | FXIA INHIBITOR AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2022-10-27 | — | — | WO | disclosed |