Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25657608 | 0.83 | KMT2A (0.42) | KMT2AFABP5FABP7POLBEPHX2 | |
| SCHEMBL25657611 | 0.82 | KMT2A (0.35) | KMT2AFABP5FABP7POLBEPHX2 | |
| SCHEMBL24964878 | 0.78 | KMT2A (0.39) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL27032770 | 0.77 | FABP5 (0.40) | KMT2AFABP5FABP7POLBEPHX2 | |
| SCHEMBL29828502 | 0.77 | FABP5 (0.40) | KMT2AFABP5FABP7POLBEPHX2 | |
| SCHEMBL25657610 | 0.77 | FABP5 (0.40) | KMT2AFABP5FABP7POLBEPHX2 | |
| SCHEMBL13327272 | 0.76 | L3MBTL1 (0.48) | KMT2AFABP5FABP7EPHX2L3MBTL1 | |
| SCHEMBL25657500 | 0.76 | KMT2A (0.40) | KMT2AFABP5FABP7POLBEPHX2 | |
| SCHEMBL24633673 | 0.76 | KMT2A (0.39) | KMT2AFABP5FABP7EPHX2TSHR | |
| SCHEMBL24633588 | 0.74 | KMT2A (0.36) | KMT2AFABP5FABP7POLBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024101402-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS | 中外製薬株式会社 | 2024-05-16 | — | — | WO | disclosed |
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |