Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14572722 | 0.84 | TDP1 (0.37) | — | |
| SCHEMBL26207916 | 0.84 | TDP1 (0.37) | — | |
| SCHEMBL16750061 | 0.84 | TDP1 (0.37) | — | |
| SCHEMBL24253077 | 0.84 | TDP1 (0.37) | — | |
| SCHEMBL26194901 | 0.82 | — | — | |
| SCHEMBL18234076 | 0.81 | EPHX1 (0.33) | — | |
| SCHEMBL15715597 | 0.81 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14558073 | 0.81 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL17154157 | 0.79 | EPHX1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL26207967 | 0.78 | AR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |