Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24634005 | 0.79 | MEN1 (0.32) | MEN1ALDH1A1KMT2A | |
| SCHEMBL15715597 | 0.79 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14558073 | 0.79 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20642385 | 0.75 | — | — | |
| SCHEMBL24634009 | 0.75 | — | — | |
| SCHEMBL18631749 | 0.73 | ACE (0.34) | EPHX1 | |
| SCHEMBL12667431 | 0.72 | MEN1 (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14524115 | 0.72 | MEN1 (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL24787855 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL15714056 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605022-B2 | Macrocyclic compounds for inhibition of inhibitors of apoptosis | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150284427-A1 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284427-A1 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS | BAX, API5, BCL2 | EPHX1 3585/4885MEN1 2634/4885ALDH1A1 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.