Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879363 | 0.83 | MEN1 (0.52) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL8104892 | 0.74 | HSD17B10 (0.44) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL5498811 | 0.74 | ACE2 (0.61) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL302850 | 0.73 | ACE2 (0.72) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL6961878 | 0.72 | CXCR4 (0.56) | HSD17B10ACE2CXCR4CYP2D6SMN1; SMN2 | |
| SCHEMBL234400 | 0.72 | CXCR4 (0.56) | HSD17B10ACE2CXCR4CYP2D6SMN1; SMN2 | |
| Trientine SCHEMBL9064137 | 0.72 | ACE2 (0.69) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL600834 | 0.72 | ACE2 (0.69) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL2138667 | 0.72 | ACE2 (0.69) | ANPEPERAP2HSD17B10ACE2MEN1 | |
| SCHEMBL6305650 | 0.72 | ACE2 (0.69) | ANPEPERAP2HSD17B10ACE2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373760-B1 | DECREASED PRESENCE OF AMINE-DERIVED CONTAMINANTS IN- AND/OR DEGRADATION OF AMINE SOLVENT SOLUTIONS | HUNTSMAN PETROCHEMICAL LLC (US) | 2016-08-03 | — | — | EP | claimed |
| US-20110232489-A1 | METHOD TO DECREASE DECOMPOSITION PRODUCTS IN SOLUTIONS THAT ABSORB ACIDIC GASES SUCH AS CARBON DIOXIDE AND THE LIKE IN THE PRESENCE OF OXYGEN | HUNTSMAN PETROCHEMICAL LLC (US) | 2011-09-29 | — | — | US | claimed |
| US-8945280-B2 | Method to decrease decomposition products in solutions that absorb acidic gases such as carbon dioxide and the like in the presence of oxygen | HUNTSMAN PETROCHEMICAL LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-20110232489-A1 | METHOD TO DECREASE DECOMPOSITION PRODUCTS IN SOLUTIONS THAT ABSORB ACIDIC GASES SUCH AS CARBON DIOXIDE AND THE LIKE IN THE PRESENCE OF OXYGEN | HUNTSMAN PETROCHEMICAL LLC (US) | 2011-09-29 | — | — | US | disclosed |