Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967445 | 0.87 | HSD17B10 (0.46) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL2463406 | 0.74 | ANPEP (0.42) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL28879363 | 0.73 | MEN1 (0.52) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL28366615 | 0.73 | HSD17B10 (0.49) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL2463408 | 0.71 | ANPEP (0.56) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL4881270 | 0.71 | HRH3 (0.39) | ALDH1A1ACE2SMN1; SMN2TSHRKDM1A | |
| SCHEMBL13185218 | 0.70 | RAD52 (0.50) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL28393236 | 0.70 | HSD17B10 (0.48) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL302850 | 0.70 | ACE2 (0.72) | HSD17B10ANPEPERAP2MEN1KMT2A | |
| SCHEMBL6839431 | 0.69 | ANPEP (0.54) | HSD17B10ANPEPERAP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015814-A | Quinazoline derivative | ZENECA LIMITED (GB) | 2000-01-18 | — | — | US | disclosed |