Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771025 | 1.00 | HPGD (0.39) | HPGDDYRK1ANPC1ALDH1A1POLB | |
| SCHEMBL24128025 | 0.89 | HPGD (0.44) | HPGDDYRK1ANPC1ALDH1A1POLB | |
| SCHEMBL29720605 | 0.89 | HPGD (0.42) | HPGDDYRK1ANPC1ALDH1A1POLB | |
| SCHEMBL24128030 | 0.89 | HPGD (0.42) | HPGDDYRK1ANPC1ALDH1A1POLB | |
| SCHEMBL24127991 | 0.88 | HPGD (0.38) | HPGDDYRK1ASMN1; SMN2 | |
| SCHEMBL24128140 | 0.87 | DYRK1A (0.35) | HPGDDYRK1ANPC1 | |
| SCHEMBL20665496 | 0.85 | HPGD (0.45) | HPGDNPC1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL29770878 | 0.83 | HPGD (0.38) | HPGD | |
| SCHEMBL24634106 | 0.83 | HPGD (0.38) | HPGD | |
| SCHEMBL20665861 | 0.80 | ALDH1A1 (0.46) | HPGDNPC1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164997-A1 | METHODS FOR THE TREATMENT OF FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2022-08-04 | — | — | WO | disclosed |