SCHEMBL24634624

SCHEMBL24634624

Cn1c(Cc2ccc(C(F)(F)F)cc2)nc2cc(O[C@H]3CC[C@@H](C(=O)O)CC3)ccc21

nearest known ligand 0.82

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ACSL1 P33121 17/20 0.82
▸ RORC P51449 1/20 0.47
▸ ACACB O00763 1/20 0.46
▸ P2RX3 P56373 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27256217 0.93 ACSL1 (0.71) ACSL1RORCACACBP2RX3
SCHEMBL27260733 0.89 ACSL1 (1.00) ACSL1
SCHEMBL24634621 0.85 ACSL1 (0.82) ACSL1
SCHEMBL24634562 0.83 ACSL1 (1.00) ACSL1
SCHEMBL27256212 0.81 ACSL1 (0.85) ACSL1P2RX3
SCHEMBL24634627 0.80 ACSL1 (1.00) ACSL1
SCHEMBL24634623 0.80 ACSL1 (1.00) ACSL1
SCHEMBL27256219 0.78 ACSL1 (0.71) ACSL1
SCHEMBL26780280 0.77 ACSL1 (0.69) ACSL1
SCHEMBL24634567 0.75 ACSL1 (0.86) ACSL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207270-A1 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM WAVEBREAK INC (US) 2024-06-27 — — US disclosed
WO-2022212568-A9 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM 1BASE PHARMACEUTICALS, LLC (US) 2023-11-16 — — WO disclosed
WO-2022212568-A1 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM 1BASE PHARMACEUTICALS, LLC (US) 2022-10-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207270-A1 COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM CPT2, PC, SREBF2 ACSL1 90/4885RORC 1956/4885ACACB 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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