Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24635743 | 0.91 | HTR2A (0.39) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL24635493 | 0.84 | TACR1 (0.39) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL24635602 | 0.76 | HSD17B10 (0.36) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL27360635 | 0.73 | HTR7 (0.42) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL25891565 | 0.67 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL25042663 | 0.66 | PARP1 (0.41) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL19216639 | 0.63 | PARP1 (0.43) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL27346755 | 0.62 | HTR7 (0.42) | HTR2AHTR2CHTR1AHTR2BHTR6 | |
| SCHEMBL261487 | 0.59 | PARP1 (0.64) | HTR1AHTR2BHTR6HTR7DRD3 | |
| SCHEMBL10817815 | 0.57 | HTR2A (0.72) | HTR2AHTR2CHTR1AHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226408-A1 | NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2022-10-27 | — | — | WO | disclosed |