Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540974 | 0.87 | PTGS1 (0.37) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL18995821 | 0.87 | PTGS1 (0.51) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL19295812 | 0.86 | PTGS1 (0.51) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL18161924 | 0.86 | HDAC1 (0.39) | PTGS1PTGS2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10021410 | 0.85 | PTGS1 (0.47) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL25113060 | 0.85 | PTGS1 (0.47) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL10021407 | 0.85 | PTGS1 (0.47) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL21388417 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL20752853 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2MGLLSMN1; SMN2FAAH | |
| SCHEMBL12659454 | 0.83 | NAMPT (0.47) | PTGS1PTGS2MGLLSMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230097252-A1 | LIGASE FUSION PROTEINS AND APPLICATION THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-03-30 | — | — | US | disclosed |
| US-20220403360-A1 | LIGASE FUSION PROTEINS AND APPLICATION THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
| US-11453870-B2 | Ligase fusion proteins and application thereof | GENEQUANTUM HEALTHCARE (SUZHOU) CO. LTD. (CN) | 2022-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230097252-A1 | LIGASE FUSION PROTEINS AND APPLICATION THEREOF | LIG1, LIG3, STUB1 | PTGS1 4352/4885PTGS2 4409/4885MGLL 1649/4885 |
| US-20220403360-A1 | LIGASE FUSION PROTEINS AND APPLICATION THEREOF | LIG1, LIG3, STUB1 | PTGS1 4352/4885PTGS2 4409/4885MGLL 1649/4885 |
| US-11453870-B2 | Ligase fusion proteins and application thereof | LIG1, LIG3, STUB1 | PTGS1 4352/4885PTGS2 4409/4885MGLL 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.