SCHEMBL24637720

SCHEMBL24637720

Cc1ccc(C2(c3ccc(C)cc3)c3cc4c(cc3-c3cc5sc(-c6cc#cs6)cc5cc32)C(c2ccc(C)cc2)(c2ccc(C)cc2)c2cc3cc(-c5ccc(/C=C6\C(=O)c7ccccc7C6=C(C#N)C#N)s5)sc3cc2-4)cc1

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
HPGD P15428 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24637735 0.86 ALDH1A1 (0.32) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL24637686 0.85 EGFR (0.41) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL24637699 0.85 ALDH1A1 (0.32) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL24637729 0.83 KMT2A (0.34) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL24637708 0.82
SCHEMBL24637719 0.82
SCHEMBL24060711 0.82
SCHEMBL20042506 0.81 EGFR (0.39)
SCHEMBL24637707 0.80 ALDH1A1 (0.33) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL24637712 0.80 KMT2A (0.34) ALDH1A1MAPTTHRBHPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3306690-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2022-09-07 EP disclosed