SCHEMBL2463784

SCHEMBL2463784

CCCC(C)(Oc1ccc(C(=O)CCc2nc(-c3ccc(C(F)(F)F)cc3)sc2C(C)C)cc1C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.46
PPARA Q07869 15/20 0.46
PPARG P37231 8/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463769 0.91 PPARA (0.54) PPARDPPARAPPARG
SCHEMBL24742008 0.88 PPARD (0.44) PPARDPPARAPPARG
SCHEMBL30004479 0.88 PPARD (0.44) PPARDPPARAPPARG
SCHEMBL12732438 0.87 PPARD (0.47) PPARDPPARAPPARG
SCHEMBL2463785 0.87 PPARD (0.38) PPARDPPARAPPARG
SCHEMBL1765922 0.85 PPARD (0.58) PPARDPPARAPPARG
SCHEMBL30003943 0.84 PPARD (0.46) PPARDPPARAPPARG
SCHEMBL24742408 0.84 PPARD (0.46) PPARDPPARAPPARG
SCHEMBL12732441 0.83 PPARD (0.51) PPARDPPARAPPARG
SCHEMBL4754234 0.83 PPARD (0.49) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1424330-B1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA NIPPON CHEMIPHAR CO (JP) 2011-09-28 EP disclosed