Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463771 | 0.91 | PPARD (0.44) | PPARDPPARACTSAPPARGWNT3A | |
| SCHEMBL2463784 | 0.87 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL1765923 | 0.85 | PPARD (0.44) | PPARDPPARAPPARGFFAR1FFAR4 | |
| SCHEMBL4754236 | 0.85 | CTSA (0.34) | PPARDPPARACTSAWNT3AS1PR1 | |
| SCHEMBL2493984 | 0.82 | CTSA (0.36) | PPARDPPARACTSAWNT3AS1PR1 | |
| SCHEMBL2462553 | 0.81 | PPARD (0.39) | PPARDPPARACTSAPPARGWNT3A | |
| SCHEMBL2463150 | 0.79 | PPARD (0.45) | PPARDPPARAPPARGWNT3A | |
| SCHEMBL2464201 | 0.78 | PPARD (0.49) | PPARDPPARACTSAPPARGWNT3A | |
| SCHEMBL2460829 | 0.77 | PPARA (0.42) | PPARDPPARAPPARGTHRATHRB | |
| SCHEMBL2463769 | 0.77 | PPARA (0.54) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |