Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614404 | 0.67 | CYP3A4 (0.46) | MAPTTP53TSHR | |
| SCHEMBL26036440 | 0.67 | PDE3B (0.44) | TTRL3MBTL1KMT2AMEN1GAA | |
| SCHEMBL31224092 | 0.67 | S100B (0.46) | TTRL3MBTL1KMT2AMEN1GAA | |
| SCHEMBL24638021 | 0.65 | POLB (0.34) | KMT2AMEN1GAAPOLBALDH1A1 | |
| SCHEMBL11373100 | 0.64 | MEN1 (0.50) | TTRL3MBTL1KMT2AMEN1PDE3B | |
| SCHEMBL2736480 | 0.63 | CYP19A1 (0.46) | MAPTL3MBTL1KMT2AMEN1POLB | |
| SCHEMBL6677065 | 0.63 | S100B (0.42) | TTRL3MBTL1KMT2AMEN1GAA | |
| SCHEMBL17576242 | 0.63 | S100B (0.57) | TTRMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL15979066 | 0.63 | KDM4E (0.44) | MAPTL3MBTL1GAAPOLBTDP1 | |
| SCHEMBL19448893 | 0.63 | KMT2A (0.49) | TTRL3MBTL1KMT2AMEN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192598-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-15 | — | — | WO | disclosed |