Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15666220 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL26964613 | 0.78 | CYP4F2 (0.44) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL1008524 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL21185054 | 0.76 | CYP4F2 (0.45) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL31691660 | 0.76 | CYP4F2 (0.40) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL26964763 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL26964696 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL13368676 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL25918978 | 0.74 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL24702054 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |