Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20574651 | 0.78 | — | — | |
| SCHEMBL3325800 | 0.76 | RPS6KA5 (0.39) | RPS6KA5TRPV1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22900755 | 0.75 | RPS6KA5 (0.38) | RPS6KA5ALDH1A1 | |
| SCHEMBL23072039 | 0.74 | P2RX7 (0.35) | — | |
| SCHEMBL15542791 | 0.73 | CYP1A2 (0.38) | ALDH1A1CYP1A2KDM4E | |
| SCHEMBL16827592 | 0.72 | SMN1; SMN2 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL2015785 | 0.72 | — | — | |
| SCHEMBL16043335 | 0.70 | MAP4K4 (0.46) | — | |
| SCHEMBL6653251 | 0.69 | KDM4E (0.35) | KDM4E | |
| SCHEMBL15974157 | 0.69 | KDM4C (0.46) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |