Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DPYD | Q12882 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085678 | 0.80 | NOTUM (0.46) | ALDH1A1DPYDUPP1KDM4EHSD17B10 | |
| SCHEMBL7705143 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ATMPARP1KDM4EHSD17B10 | |
| SCHEMBL11937456 | 0.74 | MAPT (0.35) | ALDH1A1KDM4EHSD17B10NOTUMMAPT | |
| SCHEMBL3086135 | 0.74 | POLB (0.46) | ALDH1A1KDM4EHSD17B10NOTUMMAPT | |
| SCHEMBL9788726 | 0.74 | GAA (0.47) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL442565 | 0.72 | — | — | |
| SCHEMBL11937455 | 0.71 | ALDH1A1 (0.54) | ALDH1A1ATMKDM4EMAPT | |
| SCHEMBL3092655 | 0.70 | ALDH1A1 (0.56) | ALDH1A1ATMKDM4EHSD17B10MAPT | |
| SCHEMBL262368 | 0.70 | NPC1 (0.58) | CDC7ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11937462 | 0.69 | HPGD (0.43) | ALDH1A1KDM4EMAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |