Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.34 |
| ▸ | HTR2B | P41595 | 13/20 | 0.34 |
| ▸ | HTR2A | P28223 | 10/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063769 | 1.00 | HTR2C (0.34) | HTR2CHTR2BHTR2AF2RL3CHRM4 | |
| SCHEMBL24638725 | 0.83 | MLNR (0.38) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL30932863 | 0.77 | CHRNB2 (0.42) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL24638722 | 0.77 | CHRNB2 (0.42) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL24638660 | 0.75 | HTR2C (0.43) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL24638662 | 0.75 | HTR2C (0.43) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL30932843 | 0.75 | HTR2C (0.37) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL24638721 | 0.75 | HTR2C (0.37) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL30063680 | 0.71 | HTT (0.50) | HTR2CHTR2BHTR2ACHRM4CHRM5 | |
| SCHEMBL8057128 | 0.71 | HTR2C (0.35) | HTR2CHTR2BHTR2ACHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234339-A2 | 5-HT2A AND/OR 5-HT2C RECEPTOR AGONISTS | DIAMOND THERAPEUTICS INC. (CA) | 2022-11-10 | — | — | WO | disclosed |