Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 8/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639272 | 1.00 | AXL (0.36) | AXLTIPARPKRASSOS1CYP11B2 | |
| SCHEMBL24639284 | 1.00 | AXL (0.36) | AXLTIPARPKRASSOS1CYP11B2 | |
| SCHEMBL24640612 | 0.92 | AXL (0.36) | AXLTIPARPSOS1 | |
| SCHEMBL24639261 | 0.90 | AXL (0.36) | AXLTIPARP | |
| SCHEMBL24639262 | 0.90 | AXL (0.36) | AXLTIPARP | |
| SCHEMBL24639265 | 0.82 | TIPARP (0.34) | AXLTIPARP | |
| SCHEMBL24640209 | 0.82 | TIPARP (0.34) | AXLTIPARP | |
| SCHEMBL24639244 | 0.82 | TIPARP (0.34) | AXLTIPARP | |
| SCHEMBL24640176 | 0.82 | SOS1 (0.38) | AXLTIPARPSOS1 | |
| SCHEMBL24640222 | 0.82 | SOS1 (0.38) | AXLTIPARPSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |