Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24639881 | 0.84 | — | — | |
| SCHEMBL24639974 | 0.78 | HRH3 (0.35) | HRH3 | |
| SCHEMBL24639975 | 0.78 | HRH3 (0.35) | HRH3 | |
| SCHEMBL24640000 | 0.78 | HRH3 (0.35) | HRH3 | |
| SCHEMBL24639880 | 0.77 | HRH3 (0.31) | HRH3 | |
| SCHEMBL26958276 | 0.76 | HRH3 (0.33) | HRH3 | |
| SCHEMBL31244630 | 0.76 | HTR2C (0.40) | — | |
| SCHEMBL24640313 | 0.76 | SOS1 (0.36) | HRH3 | |
| SCHEMBL24639991 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL24639976 | 0.73 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |