SCHEMBL24640639

SCHEMBL24640639

CC(C)N1CCN2c3nscc3OCC[C@H]2C1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24640638 1.00 SOS1 (0.38) SOS1
SCHEMBL24640640 0.78 SOS1 (0.38) SOS1
SCHEMBL24640623 0.78 SOS1 (0.38) SOS1
SCHEMBL24640624 0.78 SOS1 (0.38) SOS1
SCHEMBL24640038 0.77 SOS1 (0.41) SOS1
SCHEMBL24640703 0.77 SOS1 (0.41) SOS1
SCHEMBL24640702 0.77 SOS1 (0.41) SOS1
SCHEMBL24639353 0.76 SOS1 (0.41) SOS1
SCHEMBL24639358 0.76 SOS1 (0.41) SOS1
SCHEMBL24639388 0.75 TIPARP (0.45) SOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022170974-A1 TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-08-18 WO disclosed