Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640038 | 1.00 | SOS1 (0.41) | SOS1HRH3OGAHTR6HTR2A | |
| SCHEMBL24640703 | 1.00 | SOS1 (0.41) | SOS1HRH3OGAHTR6HTR2A | |
| SCHEMBL24763762 | 0.89 | SOS1 (0.35) | SOS1HRH3OGAHTR6ICMT | |
| SCHEMBL24640808 | 0.88 | LTA4H (0.37) | SOS1HRH3OGAHTR6HTR2A | |
| SCHEMBL24640717 | 0.88 | LTA4H (0.37) | SOS1HRH3OGAHTR6HTR2A | |
| SCHEMBL24640006 | 0.84 | HTR2A (0.43) | SOS1HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL24640004 | 0.84 | HTR2A (0.43) | SOS1HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL24640008 | 0.84 | HTR2A (0.43) | SOS1HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL2016209 | 0.80 | SOS1 (0.46) | SOS1HRH3 | |
| SCHEMBL24639353 | 0.80 | SOS1 (0.41) | SOS1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |