Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 11/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640017 | 1.00 | TIPARP (0.38) | TIPARPCBLBHRH3CXCR3NR1H2 | |
| SCHEMBL24640054 | 1.00 | TIPARP (0.38) | TIPARPCBLBHRH3CXCR3NR1H2 | |
| SCHEMBL24640945 | 0.83 | TIPARP (0.40) | TIPARPCBLBHRH3NR1H2NR1H3 | |
| SCHEMBL24640055 | 0.82 | HRH3 (0.37) | TIPARPHRH3CXCR3NR1H2NR1H3 | |
| SCHEMBL24640023 | 0.82 | HRH3 (0.37) | TIPARPHRH3CXCR3NR1H2NR1H3 | |
| SCHEMBL29841830 | 0.81 | TIPARP (0.41) | TIPARPCBLB | |
| SCHEMBL29088859 | 0.81 | TIPARP (0.41) | TIPARPCBLB | |
| SCHEMBL24640192 | 0.81 | TIPARP (0.49) | TIPARPCBLBHRH3NR1H2NR1H3 | |
| SCHEMBL24640233 | 0.81 | TIPARP (0.49) | TIPARPCBLBHRH3NR1H2NR1H3 | |
| SCHEMBL24640231 | 0.81 | TIPARP (0.49) | TIPARPCBLBHRH3NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |