Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 10/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640828 | 1.00 | TIPARP (0.34) | TIPARPAXLOGAKDM4E | |
| SCHEMBL24639380 | 1.00 | TIPARP (0.34) | TIPARPAXLOGAKDM4E | |
| SCHEMBL24640618 | 0.97 | TIPARP (0.34) | TIPARPAXLOGA | |
| SCHEMBL24639260 | 0.97 | TIPARP (0.34) | TIPARPAXLOGA | |
| SCHEMBL24639274 | 0.97 | TIPARP (0.34) | TIPARPAXLOGA | |
| SCHEMBL24639378 | 0.90 | HTR3A (0.35) | TIPARPAXLOGA | |
| SCHEMBL24640813 | 0.90 | HTR3A (0.35) | TIPARPAXLOGA | |
| SCHEMBL24639365 | 0.90 | PIK3CA (0.38) | TIPARPAXLOGA | |
| SCHEMBL24640826 | 0.90 | HTR3A (0.35) | TIPARPAXLOGA | |
| SCHEMBL24639344 | 0.90 | PIK3CA (0.38) | TIPARPAXLOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |