Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.31 |
| ▸ | FURIN | P09958 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24642617 | 0.95 | SIRT2 (0.36) | NMT2NMT1SIRT2GLO1EGLN1 | |
| SCHEMBL24642507 | 0.93 | NMT2 (0.33) | NMT2NMT1SIRT2FURINCTSL | |
| SCHEMBL24642530 | 0.93 | NMT2 (0.34) | NMT2NMT1SIRT2FURINCTSL | |
| SCHEMBL24642508 | 0.91 | NMT2 (0.34) | NMT2NMT1SIRT2FURINCTSL | |
| SCHEMBL24642668 | 0.90 | NMT1 (0.41) | NMT2NMT1GLO1FURINCTSL | |
| SCHEMBL24642920 | 0.88 | SIRT2 (0.34) | NMT2NMT1SIRT2 | |
| SCHEMBL24642596 | 0.85 | NMT2 (0.33) | NMT2NMT1 | |
| SCHEMBL24642677 | 0.85 | NMT2 (0.34) | NMT2NMT1SIRT2FURINCTSL | |
| SCHEMBL26504989 | 0.84 | PRKACA (0.33) | NMT2NMT1SIRT2 | |
| SCHEMBL31531931 | 0.83 | FURIN (0.31) | NMT2NMT1SIRT2FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170971-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州宜联生物医药有限公司 | 2022-08-18 | — | — | WO | disclosed |