SCHEMBL2464407

SCHEMBL2464407

CCC(Oc1ccc(C=CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)cc1C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 19/20 0.60
PPARA Q07869 16/20 0.60
PPARG P37231 9/20 0.49
FFAR1 O14842 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464409 0.87 PPARD (0.47) PPARDPPARAPPARG
SCHEMBL12648410 0.86 PPARD (0.59) PPARDPPARAPPARGFFAR1
SCHEMBL1765899 0.86 PPARD (0.59) PPARDPPARAPPARGFFAR1
SCHEMBL12648524 0.86 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL2464492 0.86 PPARD (0.61) PPARDPPARAPPARG
SCHEMBL12732404 0.85 PPARD (0.51) PPARDPPARAPPARGFFAR1
SCHEMBL12732405 0.84 PPARD (0.53) PPARDPPARAPPARGFFAR1
SCHEMBL2468604 0.84 PPARD (0.51) PPARDPPARAPPARG
SCHEMBL30004666 0.84 PPARD (0.45) PPARDPPARAPPARGFFAR1
SCHEMBL30003469 0.82 PPARD (0.47) PPARDPPARAPPARGFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1424330-B1 ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA NIPPON CHEMIPHAR CO (JP) 2011-09-28 EP disclosed