Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 13/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464407 | 0.87 | PPARD (0.60) | PPARDPPARGPPARA | |
| SCHEMBL2467495 | 0.87 | PPARD (0.45) | PPARDPPARGPPARACTSAMEN1 | |
| SCHEMBL2464495 | 0.86 | PPARA (0.46) | PPARDPPARGPPARA | |
| SCHEMBL2468608 | 0.84 | FBP1 (0.45) | PPARDPPARGPPARACTSA | |
| SCHEMBL2466103 | 0.78 | PPARD (0.41) | PPARDPPARGPPARAPTGDR2CTSA | |
| SCHEMBL2467686 | 0.76 | PPARG (0.40) | PPARDPPARGPPARAPTGDR2CTSA | |
| SCHEMBL2466352 | 0.76 | PPARD (0.40) | PPARDPPARGPPARAPTGDR2CTSA | |
| SCHEMBL2463460 | 0.75 | PPARD (0.53) | PPARDPPARGPPARAPTGDR2MEN1 | |
| SCHEMBL2465182 | 0.73 | PPARD (0.47) | PPARDPPARGPPARAPTGDR2CTSA | |
| SCHEMBL2464421 | 0.73 | PPARD (0.45) | PPARDPPARGPPARAPTGDR2CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |