Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315955 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL1294186 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL883116 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL1315957 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL3442335 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL15369826 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL8214873 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL933728 | 1.00 | HSD17B10 (0.43) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL15673396 | 0.87 | NR1H2 (0.41) | HSD17B10CHRM2CHRM1CHRM3ATM | |
| SCHEMBL193111 | 0.87 | ATM (0.59) | HSD17B10CHRM2CHRM1CHRM3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | HSD17B10 1103/4885CHRM2 4223/4885CHRM1 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.