Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.35 |
| ▸ | BPTF | Q12830 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29889437 | 0.98 | CSNK2A1 (0.36) | LOXLOXL3LOXL2ROCK1PNMT | |
| Hydrochloric Acid SCHEMBL21409012 | 0.98 | CSNK2A1 (0.36) | LOXLOXL3LOXL2ROCK1PNMT | |
| Hydrochloric Acid SCHEMBL21409087 | 0.85 | CSNK2A1 (0.36) | LOXLOXL3LOXL2ROCK1PNMT | |
| SCHEMBL24337953 | 0.83 | RECQL (0.37) | ADORA2AADORA2BUSP14ESR1RET | |
| SCHEMBL29491336 | 0.83 | RECQL (0.37) | ADORA2AADORA2BUSP14ESR1RET | |
| SCHEMBL24645437 | 0.81 | ADORA2A (0.53) | ROCK1ADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL29890527 | 0.80 | ADORA2A (0.52) | ROCK1ADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL21409055 | 0.80 | ADORA2A (0.52) | ROCK1ADORA2AADORA2B | |
| SCHEMBL15068967 | 0.77 | DDB1 (0.47) | ADORA2AADORA2BESR1NSD2 | |
| SCHEMBL23474004 | 0.75 | ADORA2A (0.44) | ADORA2AADORA2BESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | LOX 349/4885LOXL3 1257/4885LOXL2 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.