Nikethamide

Nikethamide

SCHEMBL246456

CCN(CC)C(=O)c1cccnc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.65
ALDH1A1 P00352 6/20 0.61
LMNA P02545 2/20 0.61
KDM4E B2RXH2 2/20 0.61
HPGD P15428 5/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
GAA P10253 2/20 0.53
APP P05067 1/20 0.53
HCAR3 P49019 1/20 0.53
HCAR2 Q8TDS4 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
NPSR1 Q6W5P4 3/20 0.52
MAPT P10636 2/20 0.52
GFER P55789 1/20 0.52
F7 P08709 1/20 0.52
F3 P13726 1/20 0.52
SARM1 Q6SZW1 1/20 0.52
SIRT2 Q8IXJ6 1/20 0.52
SIRT6 Q8N6T7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nikethamide SCHEMBL29754232 1.00 HTT (0.65) HTTALDH1A1LMNAKDM4EHPGD
Nikethamide SCHEMBL2477607 0.98 HTT (0.63) HTTALDH1A1LMNAKDM4EHPGD
Nikethamide SCHEMBL28425770 0.98 HTT (0.63) HTTALDH1A1LMNAKDM4EHPGD
Nikethamide SCHEMBL11145071 0.95 HTT (0.64) HTTALDH1A1LMNAKDM4EHPGD
Nikethamide SCHEMBL5964875 0.92 F7 (0.67) HTTALDH1A1LMNAKDM4EHPGD
Nikethamide SCHEMBL9541686 0.92 HTT (0.57) HTTALDH1A1LMNAKDM4EHPGD
SCHEMBL10599239 0.89 HTT (0.57) HTTALDH1A1LMNAKDM4EHPGD
SCHEMBL14855190 0.89 HTT (0.61) HTTALDH1A1LMNAKDM4EHPGD
SCHEMBL28527737 0.86 HTT (0.57) HTTALDH1A1LMNAKDM4EGAA
SCHEMBL30476608 0.84 HTT (0.63) HTTALDH1A1LMNAKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6516 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746093-A1 REFORMING SYSTEM FOR ELECTRODE ASSEMBLY AND METHOD FOR OPERATING THE SAME SK On Co., Ltd. (KR) 2026-05-20 EP claimed
US-20260135251-A1 REFORMING SYSTEM FOR ELECTRODE ASSEMBLY AND METHOD FOR OPERATING THE SAME SK ON CO LTD (KR) 2026-05-14 US claimed
US-12616738-B2 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid NOVO NORDISK A/S (DK) 2026-05-05 US claimed
EP-3350313-B1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2025-11-26 EP claimed
EP-4557951-A1 COMPOSITION COMPRISING BIODEGRADABLE MICROCAPSULES Givaudan SA (CH) 2025-05-28 EP claimed
CN-119214167-B Sludge source plant stimulant as well as directional preparation method and application thereof 同济大学 2025-05-27 CN claimed
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 US claimed
US-12292363-B2 Method for preparing biological material having excellent light-transmitting property RIKEN (JP) 2025-05-06 US claimed
CN-119557124-B Method for realizing DDS multi-core deployment on AutoSar CP platform 奥特酷智能科技(南京)有限公司 2025-04-15 CN claimed
CN-119769403-A Efficient nitrogen fixation and acid aluminum resistant sugarcane variety breeding method 广西壮族自治区农业科学院 2025-04-08 CN claimed
US-4933003-A SINGLE PHASE, HOMOGENEOUS AND HIGH SURFACE AREA THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1990-06-12 US claimed
CN-1036696-A The medicine preparation that is used for induced labor and contraception HOECHST AG (DE) 1989-11-01 CN claimed
US-4822844-A MODIFIED WITH NITROGEN COMPOUND CONTAINING EITHER OXYGEN OR SULFUR AS BRANCHING OR END GROUP THE YOKOHAMA RUBBER CO., LTD. (JP) 1989-04-18 US claimed
US-4756909-A Method for relieving pain or producing analgesia with n-butanol Avram, Elena (US) 1988-07-12 US claimed
EP-0150439-B1 AN ACID BATH FOR ELECTRODEPOSITION OF GOLD OR GOLD ALLOYS, AN ELECTROPLATING METHOD AND THE USE OF SAID BATH LeaRonal (UK) plc (GB) 1988-06-01 EP claimed
US-4695583-A Method for relieving pain or producing analgesia Avram, Elena (US) 1987-09-22 US claimed
US-4647625-A Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1987-03-03 US claimed
US-4389393-A Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose FOREST LABORATORIES, INC. (US) 1983-06-21 US claimed
EP-0079741-A2 Archival recording media with improved information layer and associated substrate UNISYS CORPORATION (US) 1983-05-25 EP claimed
WO-1983001704-A1 ARCHIVAL RECORDING MEDIA WITH IMPROVED INFORMATION LAYER AND ASSOCIATED SUBSTRATE BURROUGHS CORP (US) 1983-05-11 WO claimed