Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745639 | 0.91 | ALDH1A1 (0.52) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nikethamide SCHEMBL29754232 | 0.89 | HTT (0.65) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nikethamide SCHEMBL246456 | 0.89 | HTT (0.65) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nikethamide SCHEMBL28425770 | 0.87 | HTT (0.63) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nikethamide SCHEMBL2477607 | 0.87 | HTT (0.63) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nikethamide SCHEMBL11145071 | 0.84 | HTT (0.64) | HTTALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL28527737 | 0.83 | HTT (0.57) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nitric Acid SCHEMBL3871300 | 0.82 | HTT (0.45) | HTTALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL14855190 | 0.82 | HTT (0.61) | HTTALDH1A1KDM4ELMNANPSR1 | |
| Nikethamide SCHEMBL5964875 | 0.82 | F7 (0.67) | HTTALDH1A1KDM4ELMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161422-B1 | ALKANOLAMINE DERIVATIVES AND PLATELET AGGREGATION INHIBITORS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4619938-A | Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors | TERUMO KABUSHIKI KAISHA (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0161422-A1 | Alkanolamine derivatives and platelet aggregation inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-11-21 | — | — | EP | disclosed |