Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932458 | 1.00 | CA1 (0.67) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL6937422 | 1.00 | CA1 (0.67) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL16886879 | 0.83 | CA1 (0.71) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL18422395 | 0.83 | CA1 (0.71) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL30024474 | 0.83 | CA1 (0.71) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL18422806 | 0.83 | CA1 (0.71) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL8714843 | 0.83 | CA1 (0.57) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL5969953 | 0.82 | CA1 (0.60) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL2463172 | 0.82 | CA1 (0.60) | CA1CA2PDPK1MAOAMAOB | |
| SCHEMBL21690353 | 0.82 | CA1 (0.56) | CA1CA2PDPK1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4782252-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| EP-0738149-A4 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 1999-10-27 | — | — | EP | claimed |
| EP-0738149-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | claimed |
| US-6015822-A | ANTIULCER, ANTIDIARRHEA, AND ANTIARRHYTHMIA AGENTS; CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) | 2000-01-18 | — | — | US | disclosed |
| CN-1219533-A | Sulfonamide-substituted fused 5-membered ring compounds, their use as medicament, and pharmaceutical preparation comprising them | HOECHST MARION ROUSSEL DE GMBH (DE) | 1999-06-16 | — | — | CN | disclosed |