Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937422 | 0.83 | CA1 (0.67) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL2464696 | 0.83 | CA1 (0.67) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL6932458 | 0.83 | CA1 (0.67) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL27872462 | 0.81 | CA1 (0.57) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL13584773 | 0.81 | CA1 (0.57) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL6337843 | 0.76 | CA1 (0.71) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL30024474 | 0.76 | CA1 (0.71) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL18422395 | 0.76 | CA1 (0.71) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL16886879 | 0.76 | CA1 (0.71) | CA1CA2MAOAMAOBPDPK1 | |
| SCHEMBL18422806 | 0.76 | CA1 (0.71) | CA1CA2MAOAMAOBPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |