Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084990 | 0.88 | KMO (0.49) | CA12CA1CA9NPC1RAB9A | |
| SCHEMBL15447289 | 0.79 | SYK (0.48) | SYKNPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL19023119 | 0.77 | SYK (0.56) | SYKNPC1RAB9APOLBKDM4E | |
| SCHEMBL14564354 | 0.77 | SYK (0.48) | SYKNPC1RAB9APOLBKDM4E | |
| SCHEMBL655559 | 0.76 | CHEK1 (0.54) | SYKNPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL4300707 | 0.76 | NPC1 (0.56) | NPC1RAB9APOLBKDM4EHSD17B10 | |
| SCHEMBL23860118 | 0.74 | CA12 (0.41) | CA12CA1CA9NPC1RAB9A | |
| SCHEMBL18344998 | 0.74 | CA12 (0.43) | CA12CA1CA9RAB9A | |
| SCHEMBL23631639 | 0.74 | KMO (0.59) | SYKNPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL24648604 | 0.73 | NPC1 (0.47) | NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221960-A1 | COMPOUNDS FOR TREATING PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) MEDIATED DISEASES OR CONDITIONS | Medipure Pharmaceuticals Inc. (CA) | 2022-10-27 | — | — | WO | disclosed |